Medical research against HIV of type IIa
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The anti-HIV IIa :
H3N(+)-Ala-Asn-Thréo-D-Ile-5'-TGC-3'-Ala-Asn(D/L)-Tgc-Glu-Ser-COO(-)
where Thréo3 is : radical -CHOH-CH3(+)
and D-Ile a dextrogyre isoleucine ;
5'-TGC-3' is a DNA codon linked on 5' to the C=O of the carbonyle function of the dextrogyre Isoleucine 5 (D-Ile) by an anhydride carboxylophosphorylic (C=O)-O-(P=O(-O(-)))-O function, and the 3' carbone to the secondary amine function of the Alanine 5 (Ala) directly (C-NH).
The Asn(D/L) is, yielding two formula, either dextrogyre or levogyre.
Tgc stands for a Threonine of radical -CHOH-CH3 linked by a Van der Waals 0 link to an hydroxyle ion OH(-)
Glu 8 is -CH2-CH2-COOH and Ser 9 is of carboxylic function -COOH.
This anti-HIV is gained of anti-cancer properties and can fight HIV IIa.
This discovery is in U GPL.
I thank Mrs President Hillary Clinton for her grace and majesty.
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LANTIVIH : H2N-Leu-Ala-Asn-Thr-CO-NH-CO-NH-Val-Ile-COOH
where CO-NH-CO-NH is a link between two alpha carbone atome of L-Threonine 4 and L-Valine 5.
Thr 4 is of radical -CH=CH.(-CH3)-CH2-CH3 where "." is an electrion e(0,1,+,0)
and where His 8 is a levogyre histidine of radical -CH2-(C=CH-N-CH.-NH) with a "." standing for an electrion of charge 0 and of spin +. There is a nucleoyle n(0,1,0,+) of charge 0 and of spin +
between N and CH.
An other anti-HIV of type IIa :
H2N-Leu-Ala-Asn-Thr-Ile-Val-Ile-His-COOH
where Thr is of radical -CH2-CHOH-CH3. This is an isothreonine.
The Yoannix bears an NH2 function linked to the Leucine 1 (instead of H3N(+)).
The Alanine 18 must bear a -NH2 amine function instead of -COO(-):
NH2-Leu-Ala-Arg-Met-Glu-Leu-Ala-Ser-Glu-Arg-Ala-Asn-Thr-Ile-Ser-Ile-Asp(COOH)-Ala-NH2
Asp 17 noted Asp(-COOH) is aspartic acide.
The Shielder : to fight HIV of type IIa, must be H2N-Leu-Ala-Asn-Thr-Ile-NH-CO-Val-Ile-His-COO(-)
where Ile 5 is of radical -CH=C(-CH3)-CH2-CH3 with function -CH=C dextrogyre/levogyre.
-NH-CO- is a peptidic link inserted as (CO-NH-CO-NH), therefore between Ile 5 et Val 6.
Valine 6 is made of a -CH.(-CH3)-CH3 radical
with -CH. made of an oxydon p(0,1,+,0) linked to the carbone atome noted CH.
p(0,+,0,0) is a particule linked to a methyle function. The CH3 p(0,0) is called a "methylium" function, linked to the β carbone.
The Athena shield :
Leu-Ala-Asn-Thr-Ile-NH-CO-Val-Ile-Val-Ile-His-COO(-)
with Ile-NH-CO-Val defined as a double peptidic link (CO-NH-CO-NH). The Isoleucine 5 is of radical -CH-CH(-CH3)-CH3. The primary amine function of Leucine 1 is -NH2.
His 10 is of radical -CH2-(C=CH-N=CH.-CH-)
where CH. is a carbone atome with an hydrogene (H) and "." an electrinion e(0,0,1,+) a particle of charge 1 and of spin +.
Other invention :
H3N(+)-Ala-Asn-Thr-Ile-Val-Ile-His-COOH
with Ile 4 linked to the Val 5 by a double linkage : -CO-NH-CO-NH-
and Ile 6 as a L-aminoacide of radical -CH-CH(-CH3)-CH2-CH3 where CH-CH is an electronium link : 1 neutrino n(1,1,0,+) and a neutrinion n(1,2,+,0). The Histidine 6 is of carboxylic function -COOH.
There is adsorption of an ethyle function (U trema azote base of the RNA 3rd ribonucleotide yields a -C2H5 radical of "ethylium" amino-acide)... thanks to the CH-OH function of Threonine 3.
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H3N-ANTIVIH-COOH
Ala 1 is H3N-CH(-CH3)-CO-
and His 7 is NH-CH(-CH2-(CH=C-NH-CH=N-))-CO-
This discovery is efficient at 100 % of therapeutic effect, and 99% of prophylactic effect.
The HIV of type IIa is made of double-strand RNA. However, it could bear a single strand of DNA and, eventualy, an other random nucleic acide.
I strongly advice the use of the anti-virus synthetase (please see this).
The virus is made of an Uracile as 3rd base (RNA coding strand) instead of a Cytosine. The "U trema" is on 5 position. (respectively codon 1 and 2).
Codon 3 bears its first ribonucleotide as an Uracile, which yields a -CH(-CH3)-C2H5 modified amino-acide.
However, the Euphoria is efficient at 100,0% (curative effect) and 99% (prophylaxy effect).
Endly, one can write H3N-Ala-Asn-Thr-Ile-Val-Ile-His-COOH2(+).
This formula is afficient at 100 % by oral way.
Yoann Désir
The information in this page is under the Universal Global Public Licence : U GPL.
Some discoveries have not been checked, so this information is without any other guarantee.